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Precore/core region mutations of hepatitis B virus related t

發(fā)布時(shí)間:2020-12-09 11:58
  Despite the availability of an effective vaccine, hepatitis B virus(HBV) infection remains a major health problem, with more than 350 million chronically infected people worldwide and over 1 million annual deaths due to cirrhosis and liver cancer. HBV mutations are primarily generated due both to a lack of proofreading capacity by HBV polymerase and to host immune pressure, which is a very important factor for predicting disease progression and therapeutic outcomes. Several types of HBV precore/... 

【文章來(lái)源】:World Journal of Gastroenterology. 2016年17期 第4287-4296頁(yè)

【文章頁(yè)數(shù)】:10 頁(yè)

【參考文獻(xiàn)】:
期刊論文
[1]Development of Fok-I based nested polymerase chain reaction-restriction fragment length polymorphism analysis for detection of hepatitis B virus X region V5M mutation[J]. Hong Kim,Seok-Hyun Hong,Seoung-Ae Lee,Jeong-Ryeol Gong,Bum-Joon Kim.  World Journal of Gastroenterology. 2015(47)
[2]Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinoma[J]. Xin Zhang,Hui-Guo Ding.  World Journal of Hepatology. 2015(09)
[3]Hepatitis B virus pre S1 deletion is related to viral replication increase and disease progression[J]. Seoung-Ae Lee,Ki-Jeong Kim,Hong Kim,Won-Hyuk Choi,Yu-Sub Won,Bum-Joon Kim.  World Journal of Gastroenterology. 2015(16)
[4]Occult infection related hepatitis B surface antigen variants showing lowered secretion capacity[J]. Hong Kim,Seoung-Ae Lee,You-Sub Won,Hyun Joo Lee,Bum-Joon Kim.  World Journal of Gastroenterology. 2015(06)
[5]Hepatitis B virus genotypes:Global distribution and clinical importance[J]. Mustafa Sunbul.  World Journal of Gastroenterology. 2014(18)
[6]Hepatitis B virus mutations related to liver disease progression of Korean patients[J]. Bum-Joon Kim.  World Journal of Gastroenterology. 2014(02)



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