發(fā)布時(shí)間：2019-06-17 13:27

【摘要】：豬繁殖與呼吸綜合征(porcine reproductive and respiratory syndrome,PRRS)是由豬繁殖與呼吸綜合征病毒(Porcine reproductive and respiratory syndrome virus,PRRSV)引起的一種以導(dǎo)致懷孕母豬流產(chǎn)和仔豬呼吸困難為主要特征的疾病,PRRS已給養(yǎng)豬業(yè)造成巨大的經(jīng)濟(jì)損失。微RNA(miRNA)是一類重要的轉(zhuǎn)錄后調(diào)控基因表達(dá)的微小RNA分子,廣泛存在于各種生物體內(nèi)。文章綜述了miRNA-23、miRNA-26、miRNA-29、miRNA-125、miRNA-181、miRNA-506對(duì)PRRSV在豬肺泡巨噬細(xì)胞(porcine alveolar macrophages,PAM)或非洲綠猴腎上皮細(xì)胞(african green monkey kidney epithelial cell line,Marc-145)中復(fù)制的調(diào)控作用。
[Abstract]:Pig Reproductive and Respiratory Syndrome (porcine reproductive and respiratory syndrome,PRRS) is a disease caused by Porcine Reproductive and Respiratory Syndrome virus (Porcine reproductive and respiratory syndrome virus,PRRSV), which is characterized by abortion and dyspnea in pregnant sows. PRRS has caused great economic losses to the pig industry. MicroRNA (miRNA) is an important class of microRNA molecules that regulate the expression of post-transcriptional genes, which widely exists in various organisms. The regulatory effect of miRNA-23,miRNA-26,miRNA-29,miRNA-125,miRNA-181,miRNA-506 on replication of PRRSV in pig alveolar macrophage (porcine alveolar macrophages,PAM or African green monkey renal epithelial cell (african green monkey kidney epithelial cell line,Marc-145 is reviewed in this paper.
【作者單位】： 內(nèi)蒙古民族大學(xué)動(dòng)物科技學(xué)院;
【基金】：國家自然科學(xué)基金項(xiàng)目(31460662)
【分類號(hào)】：S852.651
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本文編號(hào)：2501022