HPV相關(guān)性口咽鱗狀細胞癌中p16免疫組化局部陽性的預(yù)后意義
發(fā)布時間：2018-12-19 21:39
【摘要】：正腫瘤抑制蛋白p16免疫組化染色是評價人乳頭狀瘤病毒(HPV)感染狀態(tài)的主要依據(jù),同時p16陽性也是提示HPV相關(guān)性口咽鱗狀細胞癌預(yù)后良好的標志物。目前p16陽性重要的評價指標包括p16陽性細胞數(shù)及陽性融合細胞數(shù),通常將75%陽性細胞定義為p16陽性,而≤25%陽性細胞定義為p16陰性,另外將50%陽性細胞且伴25%融
[Abstract]:Immunohistochemical staining of positive tumor suppressor protein p16 is the main basis for evaluating the status of (HPV) infection of human papillomavirus (HPV), and the positive expression of p16 is also a good prognostic marker for HPV associated oropharyngeal squamous cell carcinoma (OSCC). At present, the number of p16 positive cells and the number of positive fusion cells are the most important indexes for p16 positive, which usually define 75% of positive cells as p16 positive, 鈮，
本文編號：2387503
[Abstract]:Immunohistochemical staining of positive tumor suppressor protein p16 is the main basis for evaluating the status of (HPV) infection of human papillomavirus (HPV), and the positive expression of p16 is also a good prognostic marker for HPV associated oropharyngeal squamous cell carcinoma (OSCC). At present, the number of p16 positive cells and the number of positive fusion cells are the most important indexes for p16 positive, which usually define 75% of positive cells as p16 positive, 鈮，
本文編號：2387503
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